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NEUPEG - PEGYLATED FILGRASTIM
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| Pegylated Recombinant Human Granulocyte Colony Stimulating Factor (Pegfilgrastim) Injection 6mg Neupeg Injection Each 1 ml prefilled syringe contains: Pegylated Recombinant Human Granulocyte Colony Stimulating factor (rHu, GÃ, CSF) Pegfilgrastim.....6mg Description Neupeg (Pegfilgrastim) is a covalent conjugate of recombinant methionyl human G, CSF (Filgrastim) and monomethoxypolyethylene glycol. Filgrastim is a water, soluble 175 amino acid protein with a molecular weight of approximately 19 kilodaltons (kD). Filgrastim is obtained from the bacterial fermentation of a strain of Escherichia. coli transformed with a genetically engineered plasmid containing the human G-CSF gene. To produce Neupeg (Pegfilgrastim), a 20 kD monomethoxypolyethylene glycol molecule is covalently bound to the N, terminal methionyl residue of Filgrastim. The average molecular weight of Neupeg (Pegfilgrastim) is approximately 39 kD. |
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